{"product_id":"lactoferrin-250mg","title":"Lactoferrin","description":"\u003cblockquote\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cem\u003eA Freeze-Dried Immune Glycoprotein for Immune Defense, Iron Absorption \u0026amp; Reproductive Tract Health\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eLactoferrin is one of the body's most intelligent innate immune proteins, and its roles in human health go far beyond conventional immune support. This glycoprotein is found naturally in breast milk, saliva, tears, and the secretions of the reproductive tract, where it serves as a frontline defender against pathogens, a regulator of iron absorption, and a protector of the mucosal environments that matter most for fertility and implantation. Jarrow Formulas delivers lactoferrin in its apolactoferrin form, freeze-dried to preserve its delicate biological structure, at a clinically relevant 250mg dose per capsule.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eWhat Lactoferrin Does\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eLactoferrin's antimicrobial activity works through a unique mechanism: it binds iron in the surrounding environment, depriving bacteria, viruses, and fungi of the iron they need to grow and replicate. It also directly disrupts bacterial cell membranes through its peptide fragment lactoferricin B, released when gastric pepsin digests lactoferrin in the stomach. Beyond its antimicrobial role, lactoferrin modulates immune signaling, reduces inflammatory cytokine activity, supports the integrity of mucosal barriers, and promotes healthy iron absorption in the intestines.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eLactoferrin, Fertility \u0026amp; Embryo Transfer\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eLactoferrin is naturally expressed in the human endometrial glandular epithelium, where it plays a role in the innate immunity of the uterus. When the endometrial environment is disrupted by dysbiosis or chronic inflammation, implantation failure becomes more likely. Research published in the Archives of Gynecology and Obstetrics found that lactoferrin supplementation improved reproductive outcomes in women with a history of repeated implantation failure and a non-Lactobacillus-dominant bacterial flora.  \u003cspan class=\"inline-flex\" data-state=\"closed\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eAnother study found that bovine lactoferrin significantly decreased the expression of pro-inflammatory cytokines TNF-α and IL-1β in endometrial cells from patients with chronic endometritis, a condition strongly associated with implantation failure, miscarriage, and reduced live birth rates. By reducing endometrial inflammation, lactoferrin may create a more receptive uterine environment. \u003cspan class=\"inline-flex\" data-state=\"closed\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eA 2026 review published in Reproductive Sciences looked at lactoferrin as a non-hormonal candidate for endometriosis management. The review found that lactoferrin exerts anti-inflammatory, antioxidant, and antibacterial properties, making it a promising non-hormonal option that does not restrict fertility during treatment.\u003cspan class=\"inline-flex\" data-state=\"closed\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eLactoferrin \u0026amp; Vaginal Health\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eResearch suggests that patients with recurrent implantation failure have a reduced Lactobacillus population, the predominant protective bacterial species in the vagina and uterus. Lactoferrin supports a Lactobacillus-favorable environment by suppressing the pathogenic bacteria that compete with and displace beneficial flora, supporting vaginal pH balance, and reinforcing the mucosal immunity of the reproductive tract.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eWhat Lactoferrin Supports\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul dir=\"ltr\" class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3 print:block print:space-y-1\"\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eInnate immune defense through antimicrobial and antiviral activity\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eHealthy iron absorption and utilization in the intestines\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eEndometrial immune balance and reduced inflammatory cytokine activity in the uterine lining\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eA Lactobacillus-favorable vaginal and endometrial microbiome\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eReproductive outcomes in women with repeated implantation failure and reproductive tract dysbiosis\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eA non-hormonal supportive strategy for chronic endometritis and endometriosis-related inflammation\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eMucosal barrier integrity throughout the gut and reproductive tract\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eBest For\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eWomen navigating repeated implantation failure, chronic endometritis, reproductive tract dysbiosis, or endometriosis who want a non-hormonal, innate immune support strategy to complement their fertility protocol. Also a strong daily immune supplement for general mucosal immunity and healthy iron absorption.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eTake 1 capsule once daily with food, or as directed by your healthcare provider.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cem\u003eContains milk. Free from wheat, gluten, soybeans, egg, fish, shellfish, peanuts, tree nuts, and sesame. Non-GMO, gluten free, shelf-stable. Consult your healthcare provider before use if you are pregnant, nursing, under 18, or taking medications.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eSupplement Facts (per 1 capsule)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eLactoferrin (as Apolactoferrin): 250mg\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eOther ingredients: Microcrystalline cellulose, capsule (bovine gelatin), magnesium stearate (vegetable source), silicon dioxide\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003e\u003cstrong\u003eCount:\u003c\/strong\u003e 30 or 60 capsules\u003c\/p\u003e\n\u003ch4 class=\"font-claude-response-body break-words whitespace-normal\" dir=\"ltr\"\u003eReferences\u003cbr\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca rel=\"noopener\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6556345\/\" target=\"_blank\"\u003eCharacterization of Microbiota in Endometrial Fluid and Vaginal Secretions in Infertile Women with Repeated Implantation Failure\u003c\/a\u003e\u003cbr\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003c\/li\u003e\n\u003cli class=\"citation__title\"\u003e\n\u003ca rel=\"noopener\" href=\"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full\/10.1111\/jog.15897\" target=\"_blank\"\u003eThe efficacy of vaginal treatment for non-\u003ci\u003eLactobacillus\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003edominant endometrial microbiota—A case–control study\u003c\/a\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6556345\/\" target=\"_blank\"\u003eCharacterization of Microbiota in Endometrial Fluid and Vaginal Secretions in Infertile Women with Repeated Implantation Failure\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Jarrow Formulas","offers":[{"title":"Default Title","offer_id":45054108762302,"sku":"","price":68.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/2834\/0670\/files\/LACFE_021323_Front.webp?v=1785018605","url":"https:\/\/fourflowersapothecary.com\/products\/lactoferrin-250mg","provider":"Four Flowers Apothecary","version":"1.0","type":"link"}