{"product_id":"pycnogenol-50mg","title":"Pycnogenol 50mg","description":"\u003cblockquote\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cem\u003ePatented French Maritime Pine Bark Extract for Antioxidant Protection, Vascular Support \u0026amp; Women's Inflammatory Health\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003ePycnogenol® is one of the most extensively researched plant extracts, with over 40 years of clinical research and more than 160 published studies. Derived from the bark of French maritime pine trees grown along the southwest coast of France, it contains a unique combination of procyanidins, bioflavonoids, and organic acids that work together to neutralize free radicals, reduce inflammatory signaling, support the integrity of blood vessels and connective tissue, and protect cells from oxidative damage. Klaire Labs delivers it in its purest, most potent form: 50mg of standardized Pycnogenol® per capsule, with no unnecessary additives and no common allergens.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eHow Pycnogenol Works\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003ePycnogenol® is a natural nuclear factor-kappa B inhibitor, meaning it reduces chronic inflammation by blocking one of the central switches that drives inflammation. It also stimulates the production of nitric oxide to support vascular relaxation, inhibits platelet aggregation, and supports the body's own antioxidant enzymes including superoxide dismutase and glutathione peroxidase. Its proanthocyanidins bind selectively to collagen and elastin, protecting and supporting the structural integrity of blood vessels, capillaries, joints, and skin.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003ePycnogenol® \u0026amp; Endometriosis\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eFor women navigating endometriosis, Pycnogenol® has some of the most compelling evidence of any botanical. Endometriosis is fundamentally a condition of chronic inflammation, immune dysregulation, and estrogen-driven tissue proliferation, and Pycnogenol's NF-kB inhibiting and anti-inflammatory mechanisms address it at the root level.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eA 2007 study of 58 women found Pycnogenol® alone to significantly reduce the symptoms of endometriosis by 33% without disruption to the menstrual cycle, allowing women to become pregnant. Notably, five women in the study left because they became pregnant during the trial.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eA clinical study published in the International Journal of Women's Health found that oral contraceptives combined with Pycnogenol® resulted in significantly greater pain reduction than oral contraceptives alone. Most (56%) participants taking Pycnogenol® and an oral contraceptive reported a complete resolution of pain, while none of those taking an oral contraceptive alone reported full pain resolution.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eThe study was conducted in people with endometriomas and not only did Pycnogenol® lower pain, but it also lowered levels of CA125, a marker used clinically to monitor endometriosis and ovarian activity.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eWhat Pycnogenol® Supports\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eEndometriosis-related pelvic pain, menstrual cramping, and dysmenorrhea\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eChronic inflammatory conditions driven by NF-kB signaling\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eVascular integrity, capillary health, and healthy circulation\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eCollagen and connective tissue support in joints, vessels, and skin\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eAntioxidant protection and free radical neutralization\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eCardiovascular health and blood flow regulation\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eSkin elasticity and healthy aging\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eBest For\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eWomen navigating endometriosis, menstrual pain, or any condition with a chronic inflammatory component. Also an excellent daily antioxidant and vascular support formula for anyone prioritizing long-term cardiovascular and connective tissue health.\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eTake 1 capsule 1 to 4 times daily with food, or as directed by your healthcare provider. For endometriosis support, clinical studies used doses ranging from 30 to 60mg daily. Consistent daily use over several months is where the benefit is most pronounced.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cem\u003eConsult your healthcare provider before use if you are pregnant, nursing, under 18, taking prescription medications, or managing a medical condition.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eClean Credentials\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003ePycnogenol® is a registered trademark of Horphag Research with U.S. patent protection\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eFree from all common allergens including milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soy, and sesame\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eNon-GMO, vegan, no synthetic colors, flavors, or preservatives\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eSupplement Facts (per 1 capsule)\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eFrench Maritime Pine Bark Extract (Pinus pinaster), Pycnogenol®: 50mg\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003eOther ingredients: Microcrystalline cellulose, vegetarian capsule, L-leucine, silicon dioxide\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003eCount:\u003c\/strong\u003e 60 capsules\u003c\/p\u003e\n\u003ch4 class=\"font-claude-response-body break-words whitespace-normal\"\u003eResearch\u003c\/h4\u003e\n\u003cp class=\"heading-title\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17879831\/\"\u003eEffect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3873204\/\"\u003eCombining oral contraceptives with a natural nuclear factor-kappa B inhibitor for the treatment of endometriosis-related pain\u003c\/a\u003e\u003c\/p\u003e","brand":"Klaire Labs","offers":[{"title":"Default Title","offer_id":47680325255358,"sku":null,"price":58.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0623\/2834\/0670\/files\/PYC6_web.png?v=1783043180","url":"https:\/\/fourflowersapothecary.com\/products\/pycnogenol-50mg","provider":"Four Flowers Apothecary","version":"1.0","type":"link"}