Seed Daily Synbiotic

A 24-Strain Probiotic and Prebiotic for Digestive Health, Gut Barrier Integrity & Whole-Body Support

Most probiotics are designed around a single outcome and a handful of strains. Seed's DS-01® is built differently. A broad-spectrum synbiotic formulated with 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, DS-01® has been tested in multiple full-formulation, randomized, placebo-controlled clinical trials, including the largest probiotic clinical trial evaluating bloating and gas in otherwise healthy adults at the time of publication. This product has earned its reputation through research, and it shows.

What Makes DS-01® Different

Two things set this formula apart from the crowded probiotic landscape: the strains and the delivery system.

Seed's proprietary ViaCap® capsule-in-capsule technology safeguards live probiotic strains during digestion, ensuring that all 24 strains reach the colon alive, where they can be most effective. Most conventional probiotic capsules degrade significantly in stomach acid before reaching their target.

The prebiotic component is equally considered. Seed's prebiotic formulation consists of punicalagins concentrated from Indian pomegranate, biotransformed by gut microbes into powerful metabolites for human health, including urolithin A. This is a polyphenol-based prebiotic rather than a fiber-based one, providing a more targeted and sophisticated form of microbiome nourishment. 

Probiotic Blends & What They Support

DS-01® organizes its 24 strains into targeted functional blends, each addressing a specific system:

• Digestive Health Blend: Supports bowel regularity, reduces bloating, and relieves gas. Clinically validated to increase beneficial bacteria by 17x and strengthen the gut barrier by 22%
• Gut Immune Function Blend: Supports the gut-associated immune system, the largest immune organ in the body, through strain-specific immune modulation
• Gut Barrier Integrity Blend: Supports the tight junctions of the intestinal lining, reducing permeability and protecting against inflammatory triggers entering the bloodstream
• Cardiovascular Health Blend: Features Lactiplantibacillus plantarum SD-LPLDL-UK and Bifidobacterium lactis SD-MB2409-IT to support healthy cholesterol metabolism and cardiovascular function
• Micronutrient Synthesis Blend: Supports the gut's role in producing and absorbing key vitamins, including B12 and folate
• Dermatological Health Blend: Contains key strains shown to reduce visible signs of skin aging through the gut-skin axis

The Prebiotic: MAPP

Seed's Microbiota-Accessible Polyphenolic Precursors® (MAPP) delivers 400mg of Indian pomegranate extract with greater than 40% polyphenolic and phenolic bioactives. These precursors are metabolized by gut bacteria into postbiotic compounds, including urolithin A, providing an additional layer of cellular and gut-protective benefit.

Supports

• Digestive regularity and relief from bloating and gas
• Gut barrier integrity and reduced intestinal permeability
• Gut-immune function and a balanced immune response
• Cardiovascular health and healthy cholesterol metabolism
• Micronutrient synthesis and absorption
• Skin health through the gut-skin axis
• Whole-body health through microbiome optimization

Best For

Adults looking for a rigorously researched, clinically validated synbiotic that goes well beyond basic digestive support. Particularly relevant for those managing gut permeability, immune imbalance, skin conditions rooted in gut health, or anyone who wants a comprehensive daily foundation for microbiome health.

How to Use

Take 2 capsules together daily, ideally on an empty stomach. If you are prone to digestive sensitivity, start with 1 capsule for the first 3 days before progressing to the full dose. No refrigeration required.

Vegan, gluten free, non-GMO, ketogenic-compatible. Free from dairy, soy, peanuts, tree nuts, shellfish, sesame, and 14 allergen classes defined by EFSA. No binders, fillers, or preservatives. Women who are pregnant or planning a pregnancy should consult their healthcare provider before use.

Count: 60 capsules (30-day supply)